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Last updated: 2017/11/19

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ESR1 monoclonal antibody

  • Catalog # : MAB11145
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant protein of ESR1.
  • Immunogen:
  • Recombinant protein corresponding to human ESR1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:5000-1:20000)
    Western Blot (1:100-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (1% BSA, 50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of recombinant ESR1 protein with a GST tag with ESR1 monoclonal antibody (Cat # MAB11145) at 1:2000 dilution.
    Predicted band size: 55 KDa. Observed band size: 55 KDa.
  • Immunocytochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of HeLa cells using ESR1 monoclonal antibody (Cat # MAB11145) at 1:200 dilution.
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunocytochemistry
  • Immunofluorescence
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2099
  • Protein Accession#:
  • P03372;NM_000125.2
  • Gene Name:
  • ESR1
  • Gene Alias:
  • DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
  • Gene Description:
  • estrogen receptor 1
  • Gene Summary:
  • This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017718,OTTHUMP00000017719,estrogen receptor alpha
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