ACE monoclonal antibody
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant protein of ACE.
Immunogen
Recombinant protein corresponding to N-terminus of human ACE.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:5000-1:20000)
Western Blot (1:100-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of mouse kidney lysate 20 ug/lane with ACE monoclonal antibody (Cat # MAB11137) at 1:1000 dilution.
Predicted band size: 150 KDa. Observed band size: 190 KDa.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ACE
Entrez GeneID
1636Protein Accession#
P12821;NM_000789.2Gene Name
ACE
Gene Alias
ACE1, CD143, DCP, DCP1, MGC26566
Gene Description
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. [provided by RefSeq
Other Designations
CD143 antigen|angiotensin I converting enzyme|angiotensin converting enzyme, somatic isoform|carboxycathepsin|dipeptidyl carboxypeptidase 1|kininase II|peptidase P|peptidyl-dipeptidase A|testicular ECA
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Interactome
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