Anti-Rituximab monoclonal antibody, clone 10C5-3
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Specification
Product Description
Mouse monoclonal antibody raised against F(ab)2 fragment of Rituximab.
Target gene is CD20.Immunogen
F(ab)2 fragment of Rituximab.
Host
Mouse
Specificity
This antibody is able to interfere the binding between Rituximab and CD20 peptide.
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
ELISA (2 ug/mL for coating)
The optimal working dilution should be determined by the end user.Storage Buffer
In TBS, pH 8.0 (0.09% sodium azide).
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — MS4A1
Entrez GeneID
931Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Solutions to Avoid False Positives for Rituximab in Pre-Transplant Crossmatches.
Argentina Colmenero Velazquez, Ignacio Iturrieta-Zuazo, Juan Luis Valdivieso Shephard, Marisa Di Natale, Claudia Rita, Rubén Ballester González, José Luis Castañer Alabau, Israel Nieto Gañán.
Antibodies 2020 Aug; 9(3):E14.
Application：Func, Human, Serum.
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Solutions to Avoid False Positives for Rituximab in Pre-Transplant Crossmatches.
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