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Last updated: 2017/12/17
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TBX21 monoclonal antibody, clone eBio4B10

  • Catalog # : MAB11103
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against TBX21.
  • Immunogen:
  • Human TBX21 and mouse Tbx21.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Macaque, Mouse
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CD4+ T cells were sorted from mouse spleen, activated with Anti-mouse CD3 and Anti-mouse CD28, followed by culture in Th1- polarizing conditions, and re-activation with PMA and Ionomycin. Lysates from control (lane 1) or PMA and Ionomycin-re-activated (lane 2) cells were probed with TBX21 monoclonal antibody, clone eBio4B10 (Cat # MAB11103) at 2 ug/mL, and revealed with Anti-mouse IgG HRP.
  • Flow Cytometry
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Flow Cytometry
  • Gene Information
  • Gene Name:
  • TBX21
  • Gene Alias:
  • Gene Description:
  • T-box 21
  • Gene Summary:
  • This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq
  • Other Designations:
  • T-box expressed in T cells,T-cell-specific T-box transcription factor
  • Gene Information
  • Gene Name:
  • Tbx21
  • Gene Alias:
  • T-bet,TBT1,Tblym
  • Gene Description:
  • T-box 21
  • Other Designations:
  • OTTMUSP00000002150,T-box transcription factor
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