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Last updated: 2016/12/4
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PDCD1 monoclonal antibody, clone J116

  • Catalog # : MAB11090
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against PDCD1.
  • Immunogen:
  • Human PDCD1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Functional Study
  • Flow Cytometry
  • Flow Cytometry
  • Staining of human PDCD1 transfected cells with Anti- Human PDCD1 FITC (A)or PE (B). Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 5133
  • Gene Name:
  • PDCD1
  • Gene Alias:
  • CD279,PD1,SLEB2,hPD-1,hPD-l
  • Gene Description:
  • programmed cell death 1
  • Gene Summary:
  • This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
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