Staining of non-transfected (upper) and human VTCN1-transfected (bottom) HEK 293T cells with 0.125 ug of mouse IgG1 kappa isotype control purified (open histogram) or 0.125 ug of VTCN1 monoclonal antibody, clone H74 (Cat # MAB11004) (filled histogram) followed by Anti-mouse IgG biotin and streptavidin PE. Total cells were used for analysis.
B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (e.g., CD28; MIM 186760) on T lymphocytes.[supplied by OMIM
OTTHUMP00000013947,T cell costimulatory molecule B7x,immune costimulatory protein B7-H4