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Last updated: 2016/12/4
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ICOS monoclonal antibody, clone ISA-3

  • Catalog # : MAB10990
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against ICOS.
  • Immunogen:
  • Human ICOS.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 55-60
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody reacts with human ICOS. Human ICOS has a relative molecular mass of 55-60 kDa, composed of 27 kDa and 29 kDa chains.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Functional Study
  • Flow Cytometry
  • Flow Cytometry
  • Staining of CD3 + CD28 stimulated human PBMCs with Anti- human CD278 (ICOS) FITC (upper), and Anti-human CD278 (ICOS) PE (bottom). Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Functional Study
  • Gene Information
  • Gene Name:
  • ICOS
  • Gene Alias:
  • AILIM,CD278,MGC39850
  • Gene Description:
  • inducible T-cell co-stimulator
  • Gene Summary:
  • The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq
  • Other Designations:
  • activation-inducible lymphocyte immunomediatory molecule,inducible costimulator
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