Staining of normal human peripheral blood cells with 0.25 ug of mouse IgG2b kappa isotype control purified (open histogram) or 0.25 ug of CD93 monoclonal antibody, clone R139 (Cat # MAB10980) (filled histogram). Cells in the monocyte gate were used for analysis.
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq