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Last updated: 2016/12/4
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GPS2 monoclonal antibody, clone 1E2

  • Catalog # : MAB1096
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant GPS2.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 161-311 of human GPS2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG3, kappa
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of cell lysates of HeLa (100 ug) were resolved by SDS - PAGE , transferred to PVDF membrane and probed with GPS2 monoclonal antibody , clone 1E2 (1 : 500) (Cat # MAB1096). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2874
  • Gene Name:
  • GPS2
  • Gene Alias:
  • AMF-1,MGC104294,MGC119287,MGC119288,MGC119289
  • Gene Description:
  • G protein pathway suppressor 2
  • Gene Summary:
  • This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000128385,OTTHUMP00000163158
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