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Last updated: 2017/1/15
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TLR3 monoclonal antibody, clone TLR3.7

  • Catalog # : MAB10900
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against TLR3.
  • Immunogen:
  • Human TLR3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody reacts with human TLR3.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • Staining of permeabilized A-549 cell line with 1 ug of Purified mouse IgG1 kappa isotype control (open histogram) or 1 ug of TLR3 monoclonal antibody, clone TLR3.7 (Cat # MAB10900) (filled histogram) followed by Anti-mouse IgG FITC. Total cells were used for analysis.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 7098
  • Gene Name:
  • TLR3
  • Gene Alias:
  • CD283
  • Gene Description:
  • toll-like receptor 3
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq
  • Other Designations:
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