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Last updated: 2017/8/20
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ITGB3 monoclonal antibody, clone VI-PL2

  • Catalog # : MAB10888
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against ITGB3.
  • Immunogen:
  • Human ITGB3.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 90-110
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody reacts with human ITGB3, a 90-110 kDa member of the beta integrin family expressed by a wide variety of cells, including leukocytes, platelets, endothelial and smooth muscle cells.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Functional Study
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood platelets with 0.06 ug of mouse IgG1 kappa isotype control purified (upper) or 0.06 ug of ITGB3 monoclonal antibody, clone VI-PL2 (Cat # MAB10888) (bottom) followed by 'F(ab')2 Anti-mouse IgG PE followed by Anti-human CD42b FITC.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 3690
  • Gene Name:
  • ITGB3
  • Gene Alias:
  • CD61,GP3A,GPIIIa
  • Gene Description:
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • Gene Summary:
  • The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
  • Other Designations:
  • integrin beta chain, beta 3,platelet glycoprotein IIIa
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