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Last updated: 2017/5/21
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ITGAL monoclonal antibody, clone HI111

  • Catalog # : MAB10887
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against ITGAL.
  • Immunogen:
  • Human ITGAL.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 180
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody reacts with human ITGAL, the 180 kDa integrin alpha L, also known as the lymphocyte function associated antigen-1 (LFA-1) alpha chain.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Functional Study
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood cells with Anti-human ITGAL FITC.
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 3683
  • Gene Name:
  • ITGAL
  • Gene Alias:
  • CD11A,LFA-1,LFA1A
  • Gene Description:
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
  • Gene Summary:
  • ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • LFA-1 alpha,antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide,integrin alpha L,integrin gene promoter,lymphocyte function-associated antigen 1
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