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Last updated: 2016/12/4
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HLA-E monoclonal antibody, clone 3D12HLA-E

  • Catalog # : MAB10879
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against HLA-E.
  • Immunogen:
  • Human HLA-E.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody HLA-E.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood cells with 0.5 ug of mouse IgG1 kappa isotype control purified (open histogram) or 0.5 ug of HLA-E monoclonal antibody, clone 3D12HLA-E (Cat # MAB10879) (filled histogram) followed by Anti-mouse IgG biotin and streptavidin PE. Cells in the lymphocyte gate were used for analysis.
  • Application Image
  • Western Blot
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3133
  • Gene Name:
  • HLA-E
  • Gene Alias:
  • DKFZp686P19218,EA1.2,EA2.1,HLA-6.2,MHC,QA1
  • Gene Description:
  • major histocompatibility complex, class I, E
  • Gene Summary:
  • HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq
  • Other Designations:
  • HLA class I histocompatibility antigen, E alpha chain,MHC HLA-E alpha-1,MHC HLA-E alpha-2.1,MHC class I antigen,OTTHUMP00000029214,lymphocyte antigen
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