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Last updated: 2017/4/23
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CD16 monoclonal antibody, clone eBioCB16

  • Catalog # : MAB10877
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against CD16.
  • Immunogen:
  • Human CD16.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 50-80
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody recognizes CD16 (Fc gamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood cells with 0.25 ug of mouse IgG1 kappa isotype control purified (open histogram) or 0.25 ug of CD16 monoclonal antibody, clone eBioCB16 (Cat # MAB10877) (filled histogram) followed by Anti-mouse IgG FITC. Cells in the lymphocyte (upper) and granulocyte (bottom) gates were used for analysis.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2214
  • Gene Name:
  • FCGR3A
  • Gene Alias:
  • CD16,CD16A,FCG3,FCGR3,FCGRIII,FCR-10,FCRIII,FCRIIIA,IGFR3
  • Gene Description:
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Gene Summary:
  • This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Fc fragment of IgG, low affinity III, receptor for (CD16),Fc fragment of IgG, low affinity IIIa, receptor for (CD16),Fc gamma receptor III-A,Fc-gamma RIII-alpha,Fc-gamma RIIIa,Fc-gamma receptor III-2 (CD 16),Fc-gamma receptor IIIb (CD16),FcgammaRIIIA,OTTH
  • Gene Information
  • Entrez GeneID:
  • 2215
  • Gene Name:
  • FCGR3B
  • Gene Alias:
  • CD16,CD16b,FCG3,FCGR3
  • Gene Description:
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Other Designations:
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16),Fc-gamma receptor IIIb (CD 16),low affinity immunoglobulin gamma Fc region receptor III-B
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  • Interactome
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