Staining of normal human peripheral blood cells with 0.5 ug of mouse IgG1 kappa isotype control purified (open histogram) or 0.25ug of FCER2 monoclonal antibody, clone EBVCS2 (Cat # MAB10876) (filled histogram) followed by Anti-mouse IgG FITC. Cells in the lymphocyte gate were used for analysis.
The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.[supplied by OMIM
C-type lectin domain family 4, member J,CD23 antigen,Fc fragment of IgE, low affinity II, receptor for (CD23A)