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Last updated: 2016/12/4
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CSF1R monoclonal antibody, clone 12-3A3-1B10

  • Catalog # : MAB10872
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against CSF1R.
  • Immunogen:
  • Human CSF1R.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood cells with 0.5 ug of rat IgG1 kappa isotype control purified (open histogram) or 0.5 ug of CSF1R monoclonal antibody, clone 12-3A3-1B10 (Cat # MAB10872) (filled histogram) followed by Anti-rat IgG biotin and streptavidin PE. Cells in the monocyte gate were used for analysis.
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1436
  • Gene Name:
  • CSF1R
  • Gene Alias:
  • C-FMS,CD115,CSFR,FIM2,FMS
  • Gene Description:
  • colony stimulating factor 1 receptor
  • Gene Summary:
  • The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
  • Other Designations:
  • CD115 antigen,FMS proto-oncogene,McDonough feline sarcoma viral (v-fms) oncogene homolog,macrophage colony stimulating factor I receptor,soluble CSF1R variant 1
  • Interactome
  • Interactome
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