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Last updated: 2016/12/4
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CCR3 monoclonal antibody, clone eBio5E8-G9-B4

  • Catalog # : MAB10867
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against CCR3.
  • Immunogen:
  • Human CCR3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody reacts with human CCR3.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood cells with 0.5 ug of mouse IgG2b kappa isotype control purified (upper) or 0.5 ug of CCR3 monoclonal antibody, clone eBio5E8-G9-B4 (Cat # MAB10867) (bottom) followed by F(ab')2 Anti-mouse IgG PE. Cells in the large scatter population were used for analysis.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1232
  • Gene Name:
  • CCR3
  • Gene Alias:
  • CC-CKR-3,CD193,CKR3,CMKBR3,MGC102841
  • Gene Description:
  • chemokine (C-C motif) receptor 3
  • Gene Summary:
  • The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq
  • Other Designations:
  • CC chemokine receptor 3,OTTHUMP00000164718,b-chemokine receptor,eosinophil CC chemokine receptor 3,eosinophil eotaxin receptor
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