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Last updated: 2017/10/22
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CDH2 monoclonal antibody, clone 8C11

  • Catalog # : MAB10866
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against CDH2.
  • Immunogen:
  • Human CDH2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 130
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody reacts with human CDH2, also known as N-Cadherin. CD325 is a 130 kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • Staining of HeLa cells with 0.25 ug of mouse IgG1 kappa isotype control purified (open histogram) or 0.25 ug of CDH2 monoclonal antibody, clone 8C11 (Cat # MAB10866) (filled histogram) followed by F(ab')2 Anti-mouse IgG PE. Total viable cells were used for analysis.
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1000
  • Gene Name:
  • CDH2
  • Gene Alias:
  • CD325,CDHN,CDw325,NCAD
  • Gene Description:
  • cadherin 2, type 1, N-cadherin (neuronal)
  • Gene Summary:
  • This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq
  • Other Designations:
  • N-cadherin 1,cadherin 2, N-cadherin (neuronal),cadherin 2, type 1,calcium-dependent adhesion protein, neuronal,neural cadherin
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