The monoclonal antibody reacts with human CDH2, also known as N-Cadherin. CD325 is a 130 kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain.
The optimal working dilution should be determined by the end user.
In aqueous buffer (0.09% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Staining of HeLa cells with 0.25 ug of mouse IgG1 kappa isotype control purified (open histogram) or 0.25 ug of CDH2 monoclonal antibody, clone 8C11 (Cat # MAB10866) (filled histogram) followed by F(ab')2 Anti-mouse IgG PE. Total viable cells were used for analysis.
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq