Western blot analysis of HeLa cell lysate (30 ug) was resolved by SDS - PAGE , transferred to PVDF membrane and probed with CSNK2A1 monoclonal antibody , clone 3G1 (1 : 1000) (Cat # MAB1086). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq
CK2 catalytic subunit alpha,OTTHUMP00000029925,OTTHUMP00000029926,casein kinase II alpha 1 subunit,casein kinase II alpha subunit,protein kinase CK2