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Last updated: 2016/12/4
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HLA-DRA monoclonal antibody, clone LN3

  • Catalog # : MAB10849
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against HLA-DRA.
  • Immunogen:
  • Human HLA-DRA.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The antibody reacts with HLA-DRA.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Flow Cytometry
  • Flow Cytometry
  • Staining of normal human peripheral blood cells with 0.125 ug of purified mouse IgG2b isotype control (open histogram) or 0.125 ug of HLA-DRA monoclonal antibody, clone LN3 (Cat # MAB10849) (filled histogram) followed by Anti-mouse IgG FITC. Cells in the lymphocyte gate were used for analysis.
  • Application Image
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 3122
  • Gene Name:
  • HLA-DRA
  • Gene Alias:
  • HLA-DRA1
  • Gene Description:
  • major histocompatibility complex, class II, DR alpha
  • Gene Summary:
  • HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq
  • Other Designations:
  • HLA class II histocompatibility antigen, DR alpha chain,MHC cell surface glycoprotein,histocompatibility antigen HLA-DR alpha
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