NQO1 monoclonal antibody, clone 4D12
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) against A-549 (1), SKNES (2), HepG2 (3), MCF-7 (4) and HeLa (5) cell lysate.
Western Blot (Recombinant protein)
Western blot analysis using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) against human NQO1 (aa: 134-274) recombinant protein. (Expected MW is 41.3 kDa)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human testis (A) and human ovarian cancer (B) tissues using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) with DAB staining.
Enzyme-linked Immunoabsorbent Assay
ELISA measurement of NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835).
Flow Cytometry
Flow cytometric analysis of NIH/3T3 cells using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant NQO1.
Immunogen
Recombinant protein corresponding to human NQO1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) against A-549 (1), SKNES (2), HepG2 (3), MCF-7 (4) and HeLa (5) cell lysate.Western Blot (Recombinant protein)
Western blot analysis using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) against human NQO1 (aa: 134-274) recombinant protein. (Expected MW is 41.3 kDa)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human testis (A) and human ovarian cancer (B) tissues using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) with DAB staining.Enzyme-linked Immunoabsorbent Assay
ELISA measurement of NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835).Flow Cytometry
Flow cytometric analysis of NIH/3T3 cells using NQO1 monoclonal antibody, clone 4D12 (Cat # MAB10835) (green) and negative control (red). -
Gene Info — NQO1
Entrez GeneID
1728Gene Name
NQO1
Gene Alias
DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Gene Description
NAD(P)H dehydrogenase, quinone 1
Omim ID
125860Gene Ontology
HyperlinkGene Summary
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
DT-diaphorase|NAD(P)H menadione oxidoreductase 1, dioxin-inducible|NAD(P)H:Quinone acceptor oxidoreductase type 1|NAD(P)H:menadione oxidoreductase 1|NAD(P)H:quinone oxireductase|azoreductase|diaphorase (NADH/NADPH) (cytochrome b-5 reductase)|diaphorase-4|
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Interactome
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Disease
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