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MYST1 monoclonal antibody, clone 8C4C4

  • Catalog # : MAB10823
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant MYST1.
  • Immunogen:
  • Recombinant protein corresponding to human MYST1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    Immunofluorescence (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using MYST1 monoclonal antibody, clone 8C4C4 (Cat # MAB10823) against HeLa (1), HepG2 (2) and SMMC-7721 (3) cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using MYST1 monoclonal antibody, clone 8C4C4 (Cat # MAB10823) with DAB staining.
  • Immunofluorescence
  • Immunofluorescence
  • Confocal immunofluorescence analysis of Eca-109 cells using MYST1 monoclonal antibody, clone 8C4C4 (Cat # MAB10823) (green), showing nuclear localization.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • MYST1
  • Gene Alias:
  • FLJ14040,KAT8,MOF,hMOF
  • Gene Description:
  • MYST histone acetyltransferase 1
  • Gene Summary:
  • The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).[supplied by OMIM
  • Other Designations:
  • histone acetyltransferase MYST1,ortholog of Drosophila males absent on the first (MOF)
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