MSH2 monoclonal antibody, clone 1B3 (3A2B8C)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis using MSH2 monoclonal antibody, clone 1B3 (3A2B8C) (Cat # MAB10812) against HeLa (1), A-549 (2), A-431 (3) and HEK293 (4) cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer (A) and lung cancer (B) tissues, showing nuclear localization using MSH2 monoclonal antibody, clone 3A2B8C (Cat # MAB10812) with DAB staining.
Immunofluorescence
Confocal immunofluorescence analysis of HeLa cells using MSH2 monoclonal antibody, clone 1B3 (3A2B8C) (Cat # MAB10812) (green), showing nuclear localization. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
-
Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant MSH2.
Immunogen
Recombinant protein corresponding to human MSH2.
Host
Mouse
Reactivity
Human, Monkey
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis using MSH2 monoclonal antibody, clone 1B3 (3A2B8C) (Cat # MAB10812) against HeLa (1), A-549 (2), A-431 (3) and HEK293 (4) cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer (A) and lung cancer (B) tissues, showing nuclear localization using MSH2 monoclonal antibody, clone 3A2B8C (Cat # MAB10812) with DAB staining.Immunofluorescence
Confocal immunofluorescence analysis of HeLa cells using MSH2 monoclonal antibody, clone 1B3 (3A2B8C) (Cat # MAB10812) (green), showing nuclear localization. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — MSH2
Entrez GeneID
4436Gene Name
MSH2
Gene Alias
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Gene Description
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Gene Ontology
HyperlinkGene Summary
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq
Other Designations
mutS homolog 2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com