CDX2 monoclonal antibody, clone EPR2764Y
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Specification
Product Description
Rabbit monoclonal antibody raised against CDX2.
Immunogen
CDX2.
Host
Rabbit
Form
Liquid
Isotype
IgG
Quality Control Testing
Positive control use as adenocarcinoma of colon, normal colon.
Visualization at nuclear.Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (protein base, 0.09% sodium azide)
Storage Instruction
Store at 4°C is stable for 3 years.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunofluorescence
Immunofluorescence staining of CDX2 on COLO 320 HSR cells (positive) and WiDr cells (negative) using CDX2 monoclonal antibody, clone EPR2764Y (Cat # MAB10750) followed by Alexa Flour 488 conjugated donkey anti-rabbit IgG(H+L) as second antibody (Green) and DAPI for nucleus (Blue). -
Gene Info — CDX2
Entrez GeneID
1045Gene Name
CDX2
Gene Alias
CDX-3, CDX3
Gene Description
caudal type homeobox 2
Omim ID
600297Gene Ontology
HyperlinkGene Summary
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
Other Designations
OTTHUMP00000018176|caudal type homeo box transcription factor 2|caudal type homeobox transcription factor 2
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Interactome
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Disease
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