CALD1 monoclonal antibody, clone E-89
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Specification
Product Description
Rabbit monoclonal antibody raised against CALD1.
Immunogen
CALD1.
Host
Rabbit
Form
Liquid
Isotype
IgG
Quality Control Testing
Positive control use as smooth muscle from various sources including bowel, esophagus, uterus, appendix.
Visualization at cytoplasmic.Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (protein base, 0.09% sodium azide)
Storage Instruction
Store at 4°C is stable for 3 years.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
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Gene Info — CALD1
Entrez GeneID
800Gene Name
CALD1
Gene Alias
CDM, H-CAD, L-CAD, MGC21352, NAG22
Gene Description
caldesmon 1
Omim ID
114213Gene Ontology
HyperlinkGene Summary
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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