Immunohistochemical analysis of paraffin-embedded human cervical cancer (A) , human colon cancer (B) , human stomach cancer (C) and human bladder cancer (D) tissues using KRT19 monoclonal antibody, clone 4E8 (Cat # MAB10725) with DAB staining.
Immunofluorescence analysis of HepG2 cells using KRT19 monoclonal antibody, clone 4E8 (Cat # MAB10725) (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq
40-kDa keratin intermediate filament,cytokeratin 19,keratin, type I cytoskeletal 19,keratin, type I, 40-kd