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Last updated: 2017/7/23
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KCNQ1 monoclonal antibody, clone 5E12

  • Catalog # : MAB10709
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant KCNQ1.
  • Immunogen:
  • Recombinant protein corresponding to human KCNQ1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 95
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Flow cytometry (1:200-1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using KCNQ1 monoclonal antibody, clone 5E12 (Cat # MAB10709) against MCF-7 (1) and A-431 (2) cell lysate.
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using KCNQ1 monoclonal antibody, clone 5E12 (Cat # MAB10709) against human KCNQ1 (aa 229-347) recombinant protein. (Expected MW is 74.7 kDa)
  • ELISA
  • ELISA
  • ELISA measurement of KCNQ1 monoclonal antibody, clone 5E12 (Cat # MAB10709) .
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of MCF-7 cells using KCNQ1 monoclonal antibody, clone 5E12 (Cat # MAB10709) (green) and negative control (red) .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3784
  • Gene Name:
  • KCNQ1
  • Gene Alias:
  • ATFB1,FLJ26167,JLNS1,KCNA8,KCNA9,KVLQT1,Kv1.9,Kv7.1,LQT,LQT1,RWS,SQT2,WRS
  • Gene Description:
  • potassium voltage-gated channel, KQT-like subfamily, member 1
  • Gene Summary:
  • This gene encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • Jervell and Lange-Nielsen syndrome 1,kidney and cardiac voltage dependend K+ channel,long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1,slow delayed rectifier channel subunit
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