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Last updated: 2016/12/4
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HTRA2 monoclonal antibody, clone 1B3

  • Catalog # : MAB1070
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant HTRA2.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 134-458 of human HTRA2.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of 293T , MCF - 7 , HT - 29 , HL - 60 , HeLa , mouse brain , and rat brain extracts were resolved by SDS - PAGE , transferred to PVDF membrane and probed with HTRA2 monoclonal antibody , clone 1B3 (1 : 1000) (Cat # MAB1070) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • HTRA2
  • Gene Alias:
  • OMI,PARK13,PRSS25
  • Gene Description:
  • HtrA serine peptidase 2
  • Gene Summary:
  • This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq
  • Other Designations:
  • HtrA-like serine protease,Omi stress-regulated endoprotease,high temperature requirement protein A2,protease, serine, 25
  • Gene Pathway
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