INHA monoclonal antibody, clone 4A2
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant INHA.
Immunogen
Recombinant protein corresponding to human INHA.
Host
Mouse
Theoretical MW (kDa)
40
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lymphoid (upper) , ovary tumor (middle) and testicle tumor (bottom) tissues using INHA monoclonal antibody, clone 4A2 (Cat # MAB10699) with DAB staining.Immunofluorescence
Confocal immunofluorescence analysis of HeLa cells using INHA monoclonal antibody, clone 4A2 (Cat # MAB10699) (green) . Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
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Gene Info — INHA
Entrez GeneID
3623Gene Name
INHA
Gene Alias
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Gene Description
inhibin, alpha
Omim ID
147380Gene Ontology
HyperlinkGene Summary
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. [provided by RefSeq
Other Designations
A-inhibin subunit|inhibin alpha subunit
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Interactome
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Disease
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