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IGF2BP3 monoclonal antibody, clone 8F11

  • Catalog # : MAB10694
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant IGF2BP3.
  • Immunogen:
  • Recombinant protein corresponding to human IGF2BP3.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 69
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using IGF2BP3 monoclonal antibody, clone 8F11 (Cat # MAB10694) against Jurkat (1) , K-562 (2) and NTERA-2 (3) cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lung cancer (upper) and colon tumour tissues (bottom) using IGF2BP3 monoclonal antibody, clone 8F11 (Cat # MAB10694) with DAB staining.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • IGF2BP3
  • Gene Alias:
  • DKFZp686F1078,IMP-3,IMP3,KOC1,VICKZ3
  • Gene Description:
  • insulin-like growth factor 2 mRNA binding protein 3
  • Gene Summary:
  • The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq
  • Other Designations:
  • IGF II mRNA binding protein 3,IGF-II mRNA-binding protein 3,KH domain containing protein overexpressed in cancer
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