IGF2BP3 monoclonal antibody, clone 8F11
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant IGF2BP3.
Immunogen
Recombinant protein corresponding to human IGF2BP3.
Host
Mouse
Theoretical MW (kDa)
69
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using IGF2BP3 monoclonal antibody, clone 8F11 (Cat # MAB10694) against Jurkat (1) , K-562 (2) and NTERA-2 (3) cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer (upper) and colon tumour tissues (bottom) using IGF2BP3 monoclonal antibody, clone 8F11 (Cat # MAB10694) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IGF2BP3
Entrez GeneID
10643Gene Name
IGF2BP3
Gene Alias
DKFZp686F1078, IMP-3, IMP3, KOC1, VICKZ3
Gene Description
insulin-like growth factor 2 mRNA binding protein 3
Omim ID
608259Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq
Other Designations
IGF II mRNA binding protein 3|IGF-II mRNA-binding protein 3|KH domain containing protein overexpressed in cancer
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Interactome
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Disease
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