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HSPA5 monoclonal antibody, clone 4E3

  • Catalog # : MAB10689
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant HSPA5.
  • Immunogen:
  • Recombinant protein corresponding to human HSPA5.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 78
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using HSPA5 monoclonal antibody, clone 4E3 (Cat # MAB10689) against NIH/3T3 (1) , HeLa (2) and Jurkat (3) cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human thyroid tissues using HSPA5 monoclonal antibody, clone 4E3 (Cat # MAB10689) .
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3309
  • Gene Name:
  • HSPA5
  • Gene Alias:
  • BIP,FLJ26106,GRP78,MIF2
  • Gene Description:
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
  • Gene Summary:
  • When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM
  • Other Designations:
  • Heat-shock 70kD protein-5 (glucose-regulated protein, 78kD),OTTHUMP00000022124,heat shock 70kD protein 5 (glucose-regulated protein, 78kD),heat shock 70kDa protein 5
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