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Last updated: 2017/8/20
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GSTM1 monoclonal antibody, clone 1H4A4

  • Catalog # : MAB10673
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant GSTM1.
  • Immunogen:
  • Recombinant protein corresponding to human GSTM1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 26
  • Reactivity:
  • Human, Monkey
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    Flow cytometry (1:200-1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using GSTM1 monoclonal antibody, clone 1H4A4 (Cat # MAB10673) against COS-7 (1) , MCF-7 (2) , Jurkat (3) , HeLa (4) , HL7702 (5) and HepG2 (6) cell lysate.
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using GSTM1 monoclonal antibody, clone 1H4A4 (Cat # MAB10673) against human GSTM1 (aa 23-181) recombinant protein. (Expected MW is 25.7 kDa)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human rectum cancer (upper) and human liver cancer (bottom) tissues using GSTM1 monoclonal antibody, clone 1H4A4 (Cat # MAB10673) with DAB staining.
  • ELISA
  • ELISA
  • ELISA measurement of GSTM1 monoclonal antibody, clone 1H4A4 (Cat # MAB10673) .
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of Jurkat cells using GSTM1 monoclonal antibody, clone 1H4A4 (Cat # MAB10673) (green) and negative control (red) .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2944
  • Gene Name:
  • GSTM1
  • Gene Alias:
  • GST1,GSTM1-1,GSTM1a-1a,GSTM1b-1b,GTH4,GTM1,H-B,MGC26563,MU,MU-1
  • Gene Description:
  • glutathione S-transferase mu 1
  • Gene Summary:
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq
  • Other Designations:
  • GST class-mu 1,HB subunit 4,OTTHUMP00000013346,OTTHUMP00000013347,S-(hydroxyalkyl)glutathione lyase,glutathione S-alkyltransferase,glutathione S-aralkyltransferase,glutathione S-aryltransferase,glutathione S-transferase M1
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