GRIA3 monoclonal antibody, clone 1D2
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant GRIA3.
Immunogen
Recombinant protein corresponding to human GRIA3.
Host
Mouse
Theoretical MW (kDa)
101
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using GRIA3 monoclonal antibody, clone 1D2 (Cat # MAB10670) against HEK293 (1) and GRIA3-hIgGFc transfected HEK293 (2) cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissues (upper) and rat brain tissues (bottom) using GRIA3 monoclonal antibody, clone 1D2 (Cat # MAB10670) with DAB staining.Enzyme-linked Immunoabsorbent Assay
ELISA measurement of GRIA3 monoclonal antibody, clone 1D2 (Cat # MAB10670) . -
Gene Info — GRIA3
Entrez GeneID
2892Gene Name
GRIA3
Gene Alias
GLUR-C, GLUR-K3, GLUR3, GLURC, MRX94
Gene Description
glutamate receptor, ionotrophic, AMPA 3
Omim ID
305915Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq
Other Designations
OTTHUMP00000024261|OTTHUMP00000024262|dJ1171F9.1|glutamate receptor 3|glutamate receptor C|glutamate receptor subunit 3
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