GCG monoclonal antibody, clone 2F9
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant GCG.
Immunogen
Recombinant protein corresponding to human GCG.
Host
Mouse
Theoretical MW (kDa)
21
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using GCG monoclonal antibody, clone 2F9 (Cat # MAB10665) against HEK293 (1) and GCG-hIgGFc transfected HEK293 (2) cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GCG
Entrez GeneID
2641Gene Name
GCG
Gene Alias
GLP1, GLP2, GRPP
Gene Description
glucagon
Omim ID
138030Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq
Other Designations
glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2
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Interactome
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Disease
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