FGG monoclonal antibody, clone 4H9
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant FGG.
Immunogen
Recombinant protein corresponding to human FGG.
Host
Mouse
Theoretical MW (kDa)
52
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using FGG monoclonal antibody, clone 4H9 (Cat # MAB10650) against FGG recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human cerebellum (upper) and human liver cancer (bottom) tissues using FGG monoclonal antibody, clone 4H9 (Cat # MAB10650) with DAB staining.Immunofluorescence
Immunofluorescence analysis of 3T3-L1 cells using FGG monoclonal antibody, clone 4H9 (Cat # MAB10650) (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.Enzyme-linked Immunoabsorbent Assay
ELISA measurement of FGG monoclonal antibody, clone 4H9 (Cat # MAB10650) .Flow Cytometry
Flow cytometric analysis of HepG2 cells using FGG monoclonal antibody, clone 4H9 (Cat # MAB10650) (blue) and negative control (red) . -
Gene Info — FGG
Entrez GeneID
2266Gene Name
FGG
Gene Alias
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Gene Description
fibrinogen gamma chain
Omim ID
134850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
fibrinogen, gamma chain|fibrinogen, gamma polypeptide
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Interactome
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