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FBLN5 monoclonal antibody, clone 3F10A5,3F8A12

  • Catalog # : MAB10642
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant FBLN5.
  • Immunogen:
  • Recombinant protein corresponding to human FBLN5.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis using FBLN5 monoclonal antibody, clone 3F10A5,3F8A12 (Cat # MAB10642) against truncated FBLN5 recombinant protein (1) and HeLa cell lysate (2) .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human stomach carcinoma (upper) and breast carcinoma (bottom) , showing cytoplasmic localization using FBLN5 monoclonal antibody, clone 3F10A5,3F8A12 (Cat # MAB10642) with DAB staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • FBLN5
  • Gene Alias:
  • ARMD3,DANCE,EVEC,FIBL-5,FLJ90059,UP50
  • Gene Description:
  • fibulin 5
  • Gene Summary:
  • The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq
  • Other Designations:
  • developmental arteries and neural crest epidermal growth factor-like,urine p50 protein
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