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Last updated: 2017/11/19
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SNCA monoclonal antibody, clone 5C2

  • Catalog # : MAB1064
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant SNCA.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 61-95 of human SNCA.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody has the specificity against the NAC domain of SNCA.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of recombinant human synuclein family (alpha - , beta - and gamma -) and SNCA domains (1 - 60 , 1 - 95 , 61 - 140 and 96 - 140) proteins were resolved by SDS - PAGE , transferred to PVDF membrane and probed with SNCA (NAC, amino acids 61 - 95) monoclonal antibody , clone 5C2 (Cat # MAB1064) (1 : 1000) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6622
  • Gene Name:
  • SNCA
  • Gene Alias:
  • MGC110988,NACP,PARK1,PARK4,PD1
  • Gene Description:
  • synuclein, alpha (non A4 component of amyloid precursor)
  • Gene Summary:
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
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