DKK1 monoclonal antibody, clone 2H2
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant DKK1.
Immunogen
Recombinant protein corresponding to human DKK1.
Host
Mouse
Theoretical MW (kDa)
28.7
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using DKK1 monoclonal antibody, clone 2H2 (Cat # MAB10624) against HEK293 (1) and DKK1-hIgGFc transfected HEK293 cell lysate(2).Enzyme-linked Immunoabsorbent Assay
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Gene Info — DKK1
Entrez GeneID
22943Gene Name
DKK1
Gene Alias
DKK-1, SK
Gene Description
dickkopf homolog 1 (Xenopus laevis)
Omim ID
605189Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq
Other Designations
OTTHUMP00000019617|dickkopf homolog 1|dickkopf related protein-1|dickkopf-1 like
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Interactome
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Pathway
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Disease
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