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CTTN monoclonal antibody, clone 4C6

  • Catalog # : MAB10620
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CTTN.
  • Immunogen:
  • Recombinant protein corresponding to human CTTN.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 80
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) against HeLa (1) , A-431 (2) , MCF-7 (3) , SR-BR-3 (4) , HepG2 (5) and NIH/3T3 (6) cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (upper) and tonsil tissues (bottom) using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) with DAB staining.
  • ELISA
  • ELISA
  • ELISA measurement of CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2017
  • Gene Name:
  • CTTN
  • Gene Alias:
  • EMS1,FLJ34459
  • Gene Description:
  • cortactin
  • Gene Summary:
  • This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • 1110020L01Rik,ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate),oncogene EMS1
  • Interactome
  • Interactome
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