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Last updated: 2017/8/20
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TLR7 monoclonal antibody, clone 4F4

  • Catalog # : MAB1062
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TLR7.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 451-500 of human TLR7.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of human Ramos cell lysate (80 ug) were resolved by SDS - PAGE , transferred to PVDF membrane and probed with TLR7 monoclonal antibody , clone 4F4 (1 : 1000) (Cat # MAB1062). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. Arrow indicates TLR7 protein in human Ramos cells.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • TLR7
  • Gene Alias:
  • -
  • Gene Description:
  • toll-like receptor 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022919
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