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Last updated: 2016/10/16
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KDR monoclonal antibody, clone 4B4

  • Catalog # : MAB10584
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant KDR.
  • Immunogen:
  • Recombinant hIgGFc tag fusion protein corresponding to extracellular fragment at amino acids 20-764 of human KDR.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 152
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunofluorescence (1:200-1:1000)
    Flow cytometry (1:200-1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using KDR monoclonal antibody, clone 4B4 (Cat # MAB10584) against extracellular domain of human KDR (aa 20-764) .
  • Immunofluorescence
  • Immunofluorescence
  • Confocal immunofluorescence analysis of HeLa (upper) and HepG2 (bottom) cells using KDR monoclonal antibody, clone 4B4 (Cat # MAB10584) (green) . Blue: DRAQ5 fluorescent DNA dye.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HepG2 cells using KDR monoclonal antibody, clone 4B4 (Cat # MAB10584) (green) and negative control (purple) .
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3791
  • Gene Name:
  • KDR
  • Gene Alias:
  • Gene Description:
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Gene Summary:
  • Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
  • Other Designations:
  • soluble VEGFR2,vascular endothelial growth factor receptor 2
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