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AKR1C2 monoclonal antibody, clone T101

  • Catalog # : MAB10577
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant AKR1C2.
  • Immunogen:
  • Recombinant protein corresponding to human AKR1C2.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Pig
  • Specificity:
  • It recognizes the DD1 and the DD2 isoforms.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:250-1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis using AKR1C2 monoclonal antibody, clone T101 (Cat # MAB10577) on porcine liver (lane 1) and breast cancer (lane 2).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunoperoxidase staining using AKR1C2 monoclonal antibody, clone T101 (Cat # MAB10577) on formalin-fixed paraffin embedded human lung cancer tissue showing cytoplasmic localization of dihydrodiol dehydrogenase.
  • Immunofluorescence
  • Enzyme Immunoassay
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Enzyme Immunoassay
  • Gene Information
  • Entrez GeneID:
  • 1646
  • Gene Name:
  • AKR1C2
  • Gene Alias:
  • AKR1C-pseudo,BABP,DD,DD2,DDH2,HAKRD,HBAB,MCDR2
  • Gene Description:
  • aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
  • Gene Summary:
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018995,OTTHUMP00000044759,aldo-keto reductase family 1, member C2,chlordecone reductase homolog,pseudo-chlordecone reductase,trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,type II dihydrodiol dehydrogenase
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