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ADRBK1 monoclonal antibody, clone 3F8

  • Catalog # : MAB10569
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ADRBK1.
  • Immunogen:
  • Recombinant protein corresponding to human ADRBK1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Monkey, Mouse, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    Immunofluorescence (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using ADRBK1 monoclonal antibody, clone 3F8 (Cat # MAB10569) against HeLa (1), Jurkat (2), MOLT 4 (3), Raji (4), THP-1 (5), L1210 (6), COS-7 (7), PC-12 (8), and NIH/3T3 (9) cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues (A) and cervical cancer tissues (B) using ADRBK1 monoclonal antibody, clone 3F8 (Cat # MAB10569) with DAB staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of NIH/3T3 cells using ADRBK1 monoclonal antibody, clone 3F8 (Cat # MAB10569) (green). Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • ELISA
  • ELISA detection with ADRBK1 monoclonal antibody, clone 3F8 (Cat # MAB10569).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 156
  • Gene Name:
  • ADRBK1
  • Gene Alias:
  • BARK1,BETA-ARK1,FLJ16718,GRK2
  • Gene Description:
  • adrenergic, beta, receptor kinase 1
  • Gene Summary:
  • The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq
  • Other Designations:
  • beta adrenergic receptor kinase 1
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