FBLN5 monoclonal antibody, clone 1G6A4
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis using FBLN5 monoclonal antibody, clone 1G6A4 (Cat # MAB10560) against truncated FBLN5-His recombinant protein.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human colon cancer (A) and breast cancer (B) showing cytoplasmic localization with DAB staining using FBLN5 monoclonal antibody, clone 1G6A4 (Cat # MAB10560).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant FBLN5.
Immunogen
Recombinant protein corresponding to amino acids 242-448 of human FBLN5.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using FBLN5 monoclonal antibody, clone 1G6A4 (Cat # MAB10560) against truncated FBLN5-His recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human colon cancer (A) and breast cancer (B) showing cytoplasmic localization with DAB staining using FBLN5 monoclonal antibody, clone 1G6A4 (Cat # MAB10560).Enzyme-linked Immunoabsorbent Assay
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Gene Info — FBLN5
Entrez GeneID
10516Gene Name
FBLN5
Gene Alias
ARMD3, DANCE, EVEC, FIBL-5, FLJ90059, UP50
Gene Description
fibulin 5
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq
Other Designations
developmental arteries and neural crest epidermal growth factor-like|urine p50 protein
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Interactome
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Disease
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