CDKN1C monoclonal antibody, clone 3E3
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CDKN1C.
Immunogen
Recombinant protein corresponding to human CDKN1C.
Host
Mouse
Theoretical MW (kDa)
57
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using CDKN1C monoclonal antibody, clone 3E3 (Cat # MAB10550) against HEK293 (1) and CDKN1C-hIgGFc transfected HEK293 (2) cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDKN1C
Entrez GeneID
1028Gene Name
CDKN1C
Gene Alias
BWCR, BWS, KIP2, WBS, p57
Gene Description
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011736|cyclin-dependent kinase inhibitor 1C
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Interactome
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Pathway
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