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NPPB monoclonal antibody, clone 3A6F7C7

  • Catalog # : MAB10511
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of NPPB.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to human NPPB.
  • Sequence:
  • EPLQESPRPTGVWC
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using NPPB monoclonal antibody, clone 3A6F7C7 (Cat # MAB10511) with DAB staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4879
  • Gene Name:
  • NPPB
  • Gene Alias:
  • BNP
  • Gene Description:
  • natriuretic peptide precursor B
  • Gene Summary:
  • This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000002506,OTTHUMP00000044486,brain type natriuretic peptide,natriuretic protein
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