NPPB monoclonal antibody, clone 9H6B4
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using NPPB monoclonal antibody, clone 9H6B4 (Cat # MAB10510) with DAB staining.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of NPPB.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human NPPB.
Sequence
GLQEQRNHLQGKLC
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using NPPB monoclonal antibody, clone 9H6B4 (Cat # MAB10510) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NPPB
Entrez GeneID
4879Gene Name
NPPB
Gene Alias
BNP
Gene Description
natriuretic peptide precursor B
Omim ID
600295Gene Ontology
HyperlinkGene Summary
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq
Other Designations
OTTHUMP00000002506|OTTHUMP00000044486|brain type natriuretic peptide|natriuretic protein
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Interactome
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Pathway
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Disease
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