TPD52L1 monoclonal antibody, clone d1D5
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant TPD52L1.
Immunogen
Recombinant protein corresponding to amino acids 1-131 of human TPD52L1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G affinity chromatography
Isotype
IgG2b, kappa
Recommend Usage
ELISA
Flow Cytometry
Immunohistochemistry (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (10% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry of human gastric cancer tissues.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometry analysis of A431 cell line, staining at 2-5 ug for 1x106(red line) cells. The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line). -
Gene Info — TPD52L1
Entrez GeneID
7164GeneBank Accession#
NM_001003397Protein Accession#
Q16890Gene Name
TPD52L1
Gene Alias
D53, MGC8556, TPD52L2, hD53
Gene Description
tumor protein D52-like 1
Omim ID
604069Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq
Other Designations
OTTHUMP00000017133|OTTHUMP00000017135|OTTHUMP00000017136|tumor protein D52-like 2|tumor protein D53
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