ARNTL monoclonal antibody, clone 1C5
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant ARNTL.
Immunogen
Recombinant protein corresponding to human ARNTL.
Host
Mouse
Theoretical MW (kDa)
68.7
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using ARNTL monoclonal antibody, clone 1C5 (Cat # MAB10493) against ARBTL-hIgGFc transfected HEK293 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human spleen tissues using ARNTL monoclonal antibody, clone 1C5 (Cat # MAB10493).Enzyme-linked Immunoabsorbent Assay
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Gene Info — ARNTL
Entrez GeneID
406Gene Name
ARNTL
Gene Alias
BMAL1, BMAL1c, JAP3, MGC47515, MOP3, PASD3, TIC, bHLHe5
Gene Description
aryl hydrocarbon receptor nuclear translocator-like
Omim ID
602550Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ARNT-like protein 1, brain and muscle|bHLH-PAS protein JAP3|basic-helix-loop-helix-PAS orphan MOP3|member of PAS superfamily 3
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Interactome
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Pathway
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Disease
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