Western blot analysis using APOA4 monoclonal antibody, clone 2D1C9 (Cat # MAB10488) against truncated APOA4-His recombinant protein (1),truncated APOA4(aa 21-396)-hIgGFc transfected CHO-K1 cell lysate(2),human serum (3) and human plasma (4).
Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq